catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
demean
The definition for demean is "To lower status." Used in a sentence: The embarrassing photograph demeaned the candidate in the eyes of the voters.
exalt
The definition for exalt is "To elevate by praise." Used in a sentence: The fireman was publicly exalted for his heroism.
flaw
The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.
preclude
The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.