catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
moderate
The definition for moderate is "Tending toward the average." Used in a sentence: The best–selling writer was disappointed; his new novel was only a moderate success.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
stifle
The definition for stifle is "To repress or discourage." Used in a sentence: Amy tried ineffectively to stifle her giggles after she read Susan's note in class.