disdain
The definition for disdain is "Feeling of contempt." Used in a sentence: The arrogant writer did not hide his disdain for his uneducated dinner companion.
drub
The definition for drub is "To defeat decisively." Used in a sentence: The powerful young boxer drubbed the longtime champion.
dubious
The definition for dubious is "Questionable." Used in a sentence: Karl found Kevin's claim that he was sick dubious, as he had just seen him playing football.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
genial
The definition for genial is "Sympathetic, friendly." Used in a sentence: The genial host warmly greeted his many guests.