futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
mandate
The definition for mandate is "An official order or commission to do something." Used in a sentence: Martha reluctantly obeyed the mandate to vacate her apartment.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.
periodic
The definition for periodic is "Occurring at regular intervals." Used in a sentence: The periodic innterruptions of the cuckoo clock prevented Li from concentrating.
prune
The definition for prune is "To reduce by removing excess." Used in a sentence: The candidate pruned his speech so he would not exceed the time limit.