futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
genial
The definition for genial is "Sympathetic, friendly." Used in a sentence: The genial host warmly greeted his many guests.
manifest
The definition for manifest is "Obvious." Used in a sentence: James finally made his affection manifest when he handed Jessica a red rose.
melee
The definition for melee is "A tumultuous fight among several people." Used in a sentence: After the game, a melee broke out between fans of the opposing teams.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.