catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
exasperation
The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.
exception
The definition for exception is "A case to which the rule does not apply." Used in a sentence: The teacher made an exception and let Gina eat her snack in class.
methodical
The definition for methodical is "Performed in an orderly manner." Used in a sentence: Oscar's methodical approach exasperated his free–spirited friend Ben.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.