egotist
The definition for egotist is "Self–important person." Used in a sentence: Darren dreaded carpooling with the egotist Shelly, who talked about herself nonstop.
flaw
The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.
mediate
The definition for mediate is "To come between parties in order to reconcile." Used in a sentence: The diplomatic Henry was able to mediate between the quarreling sisters.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
preclude
The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.