gargantuan
The definition for gargantuan is "Gigantic." Used in a sentence: The gargantuan monster towered over the ten–story bulding.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
onset
The definition for onset is "Beginning." Used in a sentence: Crocuses bloom at the onset of spring, sometimes even before the snow melts.
preclude
The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.
refurbish
The definition for refurbish is "To brighten or freshen." Used in a sentence: Leeanne cleaned and mended all weekend to refurbish the shabby apartment.