The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.

The definition for melee is "A tumultuous fight among several people." Used in a sentence: After the game, a melee broke out between fans of the opposing teams.

The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.

The definition for preclude is "To rule out in advance." Used in a sentence: "Having cake now will preclude dessert later," said Amber's mother.

The definition for turpitude is "Essential baseness, depravity." Used in a sentence: The turpitude of the villain in the movie offended most audiences.