grandiose
The definition for grandiose is "With an affectation of grandeur." Used in a sentence: The sweeping, grandiose staircase looked preposterous in the modest entry hall.
inauspicious
The definition for inauspicious is "Not favorable." Used in a sentence: Gary believed the black foreboding sky was an inauspicious sign.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
straddle
The definition for straddle is "To favor opposing sides." Used in a sentence: Kia straddled the issue, not wanting to say whether James or Tara was right.