catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
distortion
The definition for distortion is "The act of twisting out of shape." Used in a sentence: The story about the actress in the gossip column was a distortion of the truth.
grandiose
The definition for grandiose is "With an affectation of grandeur." Used in a sentence: The sweeping, grandiose staircase looked preposterous in the modest entry hall.
placebo
The definition for placebo is "An inactive substance used in medical testing." Used in a sentence: Tom, who had taken the placebo, found that his allergy symptoms did not go away.
turmoil
The definition for turmoil is "Extreme confusion, agitation." Used in a sentence: The windstorm caused such turmoil in the lake that the sailboat capsized.