exasperation
The definition for exasperation is "The state of being irritated." Used in a sentence: The longer Jorge waited in line at the ticket counter, the more his exasperation grew.
flaw
The definition for flaw is "An imperfection." Used in a sentence: The otherwise perfect diamond had a tiny flaw that reduced its value.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
liability
The definition for liability is "A person or thing whose presence or behavior is likely to cause embarrassment or put one at a disadvantage." Used in a sentence: Kevin's growing fatigue was a liability as he attempted to climb the steep hill.
negate
The definition for negate is "To make invalid." Used in a sentence: Paula negated Tiffany's argument by proving that her main premise was false.