catastrophic
The definition for catastrophic is "Relating to extreme misfortune." Used in a sentence: The effects of the massive hurricane were catastrophic.
disdain
The definition for disdain is "Feeling of contempt." Used in a sentence: The arrogant writer did not hide his disdain for his uneducated dinner companion.
duplicity
The definition for duplicity is "Deceptive thought, speech, or action." Used in a sentence: The life of an undercover detective is filed with necessary duplicity.
futile
The definition for futile is "Without purpose, completely ineffective." Used in a sentence: Arguing with Andrew is futile because he never changes his mind.
stifle
The definition for stifle is "To repress or discourage." Used in a sentence: Amy tried ineffectively to stifle her giggles after she read Susan's note in class.